In the final regression model, age [adjusted OR = 1.05 (1.041.07)], gender [adjusted OR = 2.32 (1.423.80)], number of combined oral drugs [adjusted OR = 1.84 (1.622.10)], and history of gastrointestinal disorders [adjusted OR = 6.22 (3.4911.11)] were associated with GISEs caused by GLP-1RAs
Waist Circumference Tirzepatide 5, 10 and 15 mg were associated with statistically greater reductions in waist circumference versus liraglutide (MD 7.02, 11.79 and 12.30 cm, respectively)
Many diverticula are seen in the sigmoid
DAC (Drug Affinity Complex) binds to albumin in the bloodstream, which dramatically extends the peptide's half-life
For kinetic experiments with fecal communities, fecal slurries prepared as described above were used instead of starter cultures